Postdoctoral scholar Dr. Dmytro Havrylyuk received an award for the poster “Ru(II) CYP1B1 Inhibitor Prodrugs with Enhanced Potency” at the 2018 Metals in Medicine, Gordon Research Conference. The project was performed in collaboration with Kimberly Stevens and Catherine A. Denning in the laboratories of Dr. David K. Heidary and Prof. Edith C. Glazer
A research study performed by Dr. Dmytro Havrylyuk, Dr. David Heidary, Leona Nease, Dr. Sean Parkin, and Dr. Edith Glazer was profiled on the back cover of the journal The European Journal of Inorganic Chemistry for a special cluster issue titled "Metal Anticancer Complexes – Activity, Mechanism of Action and Future Perspectives".
A publication authored by Dr. Erin Wachter, Mr. Diego Moya, and Prof. Edith Glazer was profiled on the cover of ACS Combinatorial Science.
Prof. Edith (Phoebe) Glazer has been invited to present the work of her research group at the International Symposium on Photopharmacology at the University of Groningen, The Netherlands. The symposium, organized by Prof.
Christine Cardin will be presenting a Nietzel Visiting Distinguished Faculty Program Seminar titled, "X-ray Crystallography and infrared transient spectroscopy with nucleic acid crystals."
Abstract: Photoactive ruthenium polypyridyl complexes attract worldwide attention because of their potential applications in cancer chemotherapy and because they provide useful tools for studying the fundamentals of electron transfer in DNA. In this talk, the structures of several ruthenium complexes bound to several oligonucleotides will be described. The recent transient infrared spectroscopy (TRIR) study of the photooxidizing [Ru(TAP)2dppz]2+ complex crystallized with the decamer duplex d(TCGGCGCCGA)2 has provided an insight into the earliest steps in guanine photooxidation and hence, DNA damage.
