Abstract: Plastic semiconductors incorporated into transistors have shown enormous potential for flexible, printable electronics as well as bioelectronics that communicate with the body. In my talk I will discuss the background and potential applications of these exotic transistors, as well as novel, state-of-the-art materials systems I have developed to overcome their intrinsic bottlenecks. I will show how these simple, low-cost solutions to organic transistor problems work towards the realization of a broad suite of organic electronic technologies.