Dmytro Havrylyuk

  • Postdoctoral Scholar
  • Chemistry
CP-148A
859-576-2162
Education

Ph.D. Danylo Halytsky Lviv National Medical University (DH LNMU), Lviv, Ukraine, 2007

Research

Medicinal chemistry, organic and inorganic synthesis

Graduate Training

Pharmacy

Selected Publications: 

Selected publications prior to UK:

1. Havrylyuk D., Zimenkovsky B., Lesyk R. Synthesis, biological activity of thiazolidinones bearing indoline moiety and isatin based hybrids. Mini-Reviews in Organic Chemistry, 2015, 12, 66-87.

2. Havrylyuk D., Zimenkovsky B., Karpenko O., Grellier P., Lesyk R. Synthesis of pyrazoline-thiazolidinone hybrids with trypanocidal activity. European Journal of Medicinal Chemistry, 2014, 85, 245-254.

3. Avdieiev S., Gera L., Hodges R.S., Havrylyuk D., Lesyk R., Ribrag V., Vassetzky Y., Kavsan V. Bradykinin antagonists and thiazolidinone derivatives as new potential anti-cancer compounds. Bioorganic & Medicinal Chemistry. 2014, 22, 3815–3823. 4

4. Havrylyuk D., Zimenkovsky B., Vasylenko O., Lesyk R. Synthesis, anticancer and antiviral activity of new 2- pyrazoline substituted 4-thiazolidinones. J. Heterocyclic Chem. 2013, 50, E55-E62.

5. Havrylyuk D., Zimenkovsky B., Vasylenko O., Day C.W., Smee D.F., Grellier P., Lesyk R. Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones. European Journal of Medicinal Chemistry. 2013, 66, 228-237.

6. Havrylyuk D., Zimenkovsky B., Vasylenko O., Gzella A., Lesyk R. Synthesis of new 4-thiazolidinone, pyrazoline, and isatin-based conjugates with promising antitumor activity. J. Med. Chem. 2012, 55, 8630−8641.

7. Havrylyuk D., Kovach N.,Zimenkovsky B., Vasylenko O.,Lesyk R. Synthesis and anticancer activity of isatin-based pyrazolines and thiazolidines conjugates. Arch. Pharm. Chem. LifeSci. 2011, 344, 514–522.

8. Havrylyuk D., Mosula L., Zimenkovsky B., Vasylenko O., Gzella A., Lesyk R. Synthesis and anticancer activity evaluation of 4-thiazolidinones containing benzothiazole moiety. European Journal of Medicinal Chemistry. 2010, 45, 5012-5021.

9. Havrylyuk D., Zimenkovsky B., Vasylenko O., Zaprutko L., Gzella A., Lesyk R. Synthesis of novel thiazolone-based compounds containing pyrazoline moiety and evaluation of their anticancer activity. European Journal of Medicinal Chemistry, 2009, 44(4), 1396-1404.

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