Simulation of P2X-mediated calcium signalling in microglia.

TitleSimulation of P2X-mediated calcium signalling in microglia.
Publication TypeJournal Article
Year of Publication2019
JournalThe Journal of physiology
Volume597
Issue3
Pagination799-818
ISSN0022-3751
Abstract

A computational model of P2X channel activation in microglia was developed that includes downfield Ca -dependent signalling pathways. This model provides quantitative insights into how diverse signalling pathways in microglia converge to control microglial function.

URLhttps://doi.org/10.1113/JP277377
DOI10.1113/JP277377
Short TitleJ Physiol
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